Research Scientist - in vitro cellular profiling of therapeutic OLIGOs

AstraZeneca AB Göteborg, Västra Götalands län, Sverige Publicerat 23 augusti 2026
full_timeonsitemid
the opportunity to apply proven molecular biology and cell biology expertise to contribute to the discovery and development of **therapeutic oligonucleotides**, such as **antisense oligonucleotides (ASOs)** and **small interfering RNA (siRNA)**, and their **Targeted Delivery** to relevant tissue, in a highly collaborative environment. The successful candidate demonstrates a passion for delivery to team objectives, combined with strong team working ethics, and thrives from working in drug discovery projects. You will join a team whose remit is to support our drug discovery projects globally with early DMPK assessment, SAR profiling and in-depth mechanism of action data. We offer a highly rewarding scientific environment with ample learning opportunities. The role is located at our vibrant R&D site in **Gothenburg, Sweden**. You will be strongly encouraged and supported to think creatively in our dynamic environment. Here, we are free from fear of failure, free to ask the right questions and make bold decisions. **What you will do:** This is a **lab-based role** focused on generating in vitro data on therapeutic oligonucleotides in support of drug discovery projects. The work includes independent troubleshooting and timely reporting of data according to agreed timelines. All work is conducted in dialog with project teams, where you are expected to present and contribute in advancing the project science, specifically in support of the Cardiovascular, Renal and Metabolism as well as Respiratory & Immunology disease area organizations. For this role, we seek a candidate with experience in the development and/or application of assays for quantitative measurements of RNA transcripts. The candidate will reinforce our team for discovery and development of therapeutic oligonucleotides. **Essential for the role:** - MSc degree in Biology or related Science - 1 to 3 years of additional experience in Biotech/Pharma or Academia - Excellent communication skills and an ability to operate effectively in a multi-disciplinary research environment - Knowledge of oligonucleotide modalities - Experience in the development and/or application of assays for quantitative measurements of RNA transcripts - Independent analysis and evaluation of complex data and delivery of data to agreed timelines **Desirable for the role:** - Coding and AI experience would be an advantage - An innovative mindset is highly valued **Why AstraZeneca in Gothenburg?** You can ask anybody who has ever set foot here – our Gothenburg site has a vibrant culture that pulls you in! It is a mix of both local and international talent. We welcome the contribution of people from all backgrounds, beliefs and walks of life. **What’s next?** If this sounds like your next challenge - please apply today! We look forward to your application, but please send it to us no later than **September 4, 2026**. **Date Posted** 24-aug.-2026 **Closing Date** 04-sep.-2026 Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. ### About Us AstraZeneca är ett globalt, innovationsdrivet bioläkemedelsföretag som inspireras av vetenskapens möjligheter. Vår drivkraft är att uppfylla patientens behov inom våra terapeutiska kärnområden. Med vårt djärva tankesätt arbetar vi proaktivt med att genomföra upptäckter bortom fantasins gränser. På olika platser runtom i världen sammanför vi team som präglas av samarbetsanda för att omvandla fantastiska idéer till läkemedel som kan förändra liv. Vi förstärker vår produktportfölj och drar nytta av potentialen med en processlinje i alla stadier av läkemedelsutvecklingen. Du blir en del av ett team som ständigt utmanar vetenskapens gränser och bidrar till att det som var omöjligt igår ses som morgondagens standard. Delar du vårt fokus och vår passion? I så fall ska du börja arbeta hos oss och hjälpa oss göra skillnad för patienter. I gengäld hjälper vi dig att utvecklas mer än du trodde var möjligt. Mer information ### Championing Inclusion and Diversity Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. Mer information ### Life at AstraZeneca We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. 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