Senior Scientist I, Early Target Generation

Responsibilities:  Strategically engaged at the early exploratory stages of target selection within the Immunology and Neuroscience therapeutic areas  Recombinant protein expression of antigens and cytokines supporting exploratory Immunology and Neuroscience therapeutic areas  Innovatively design and produce soluble and membrane protein targets with enhanced stability for functional studies and antibody discovery  Collaboration with Immunology and Neuroscience colleagues as representative of Protein Sciences, fostering the generation of innovative ideas and solutions  Contribute to scientific excellence through dedication to multiple projects simultaneously, in a fast-paced, multi-disciplinary environment  Demonstration of strong organizational and record keeping skills, ensuring timely delivery of requested material  Clearly and effectively explain research findings and strategies, prioritizing transparency   Collaborate with protein vendors and Contract Research Organizations (CROs) to secure, produce, and evaluate high-quality antigens  Cultivate innovative problem-solving by generating original technical ideas and responding to scientific, regulatory, and competitive developments  Maintain a strong knowledge of relevant publications pertaining to technological advancements, with an eye towards improving our workflows  Ph.D., M.S. or B.S. in Biochemistry, Molecular and Cell Biology or related disciplines with typically 0-4 (Ph.D), 8-10 (M.S.), or 10-12+ (B.S.) years of experience  Hands-on experience with mammalian suspension cell culture (HEK293 and CHO preferred) transient transfection, harvest and expression profiling is required  Strong molecular biology skills and experience with sequencing tools and construct design is required (Geneious, Genedata)  Experience using and interpreting standard protein analytical techniques (SDS-PAGE, Western blotting, BCA assays, endotoxin readings, size exclusion chromatography) is required  Experience with a broad spectrum of protein purification techniques (affinity, ion exchange, size exclusion chromatography, etc), preferably using AKTA instrumentation is a plus  Experience applying AI/ML workflows to improve laboratory workflows is desired  Expertise in navigating and managing relationships with different protein vendors and CROs, ensuring alignment with project goals and timelines, is a plus   Experience using GeneData Biologics is a plus  Strong Immunology and/or Neuroscience background is a plus  Experience in protein expression from e. coli is a plus  Proven research excellence demonstrated through a strong track record of publications, presentations and scientific achievements  Demonstrated ability to actively participate and collaborate across cross-functional teams  Key Competencies:  Builds strong relationships with peers and cross-functionally with partners outside the team to deliver high performance  Learns fast, grasps the "essence" and can change course quickly where indicated  Raises the bar and is never satisfied with the status quo  Creates a learning environment, open to suggestions and experimentation for improvement  Embraces the ideas of others, nurtures innovation and manages innovation to reality  AbbVie is committed to fostering an inclusive and diverse work environment. Be part of our team that is curious, open-minded, and ready to tackle the biotherapeutic challenges of tomorrow!  About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at  www.abbvie.com . Follow @abbvie on  LinkedIn,   Facebook ,  Instagram ,  X  and  YouTube. ​Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​ The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​ We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​ This job is eligible to participate in our short-term incentive programs. ​ Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of  any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. ​ AbbVie is an equal opportunity employer and is committed to operating w